C C There are a total of 1 entries in the algebraic variable array. C There are a total of 14 entries in each of the rate and state variable arrays. C There are a total of 20 entries in the constant variable array. C C C VOI is time in component environment (second). C STATES(1) is Fe3 in component Fe3 (micromolar). C CONSTS(1) is Arg in component model_constants (micromolar). C STATES(2) is Fe3_Arg in component Fe3_Arg (micromolar). C STATES(3) is Fe3_NO in component Fe3_NO (micromolar). C STATES(4) is Fe2_NO in component Fe2_NO (micromolar). C CONSTS(2) is O2 in component model_constants (micromolar). C CONSTS(3) is k1 in component model_constants (second_order_rate_constant). C CONSTS(4) is k_1 in component model_constants (first_order_rate_constant). C CONSTS(5) is k2 in component model_constants (first_order_rate_constant). C CONSTS(6) is k13 in component model_constants (first_order_rate_constant). C CONSTS(7) is k12 in component model_constants (second_order_rate_constant). C CONSTS(8) is k3 in component model_constants (first_order_rate_constant). C STATES(5) is Fe2 in component Fe2 (micromolar). C STATES(6) is Fe2_Arg in component Fe2_Arg (micromolar). C CONSTS(9) is k_4 in component model_constants (first_order_rate_constant). C CONSTS(10) is k4 in component model_constants (second_order_rate_constant). C STATES(7) is Fe3_O2_Arg in component Fe3_O2_Arg (micromolar). C CONSTS(11) is k5 in component model_constants (second_order_rate_constant). C CONSTS(12) is k_5 in component model_constants (first_order_rate_constant). C CONSTS(13) is k6 in component model_constants (first_order_rate_constant). C STATES(8) is Fe3_NOHA in component Fe3_NOHA (micromolar). C CONSTS(14) is k7 in component model_constants (first_order_rate_constant). C STATES(9) is Fe2_NOHA in component Fe2_NOHA (micromolar). C STATES(10) is NOHA in component NOHA (micromolar). C STATES(11) is Fe3_O2_NOHA in component Fe3_O2_NOHA (micromolar). C CONSTS(15) is k9 in component model_constants (second_order_rate_constant). C CONSTS(16) is k_9 in component model_constants (first_order_rate_constant). C CONSTS(17) is k_8 in component model_constants (first_order_rate_constant). C CONSTS(18) is k8 in component model_constants (second_order_rate_constant). C CONSTS(19) is k10 in component model_constants (first_order_rate_constant). C CONSTS(20) is k11 in component model_constants (first_order_rate_constant). C STATES(12) is NO in component NO (micromolar). C ALGBRC(1) is dNOdt in component NO (flux). C STATES(13) is citrulline in component citrulline (micromolar). C STATES(14) is NO3 in component NO3 (micromolar). C RATES(1) is d/dt Fe3 in component Fe3 (micromolar). C RATES(2) is d/dt Fe3_Arg in component Fe3_Arg (micromolar). C RATES(5) is d/dt Fe2 in component Fe2 (micromolar). C RATES(6) is d/dt Fe2_Arg in component Fe2_Arg (micromolar). C RATES(7) is d/dt Fe3_O2_Arg in component Fe3_O2_Arg (micromolar). C RATES(8) is d/dt Fe3_NOHA in component Fe3_NOHA (micromolar). C RATES(9) is d/dt Fe2_NOHA in component Fe2_NOHA (micromolar). C RATES(11) is d/dt Fe3_O2_NOHA in component Fe3_O2_NOHA (micromolar). C RATES(3) is d/dt Fe3_NO in component Fe3_NO (micromolar). C RATES(4) is d/dt Fe2_NO in component Fe2_NO (micromolar). C RATES(12) is d/dt NO in component NO (micromolar). C RATES(13) is d/dt citrulline in component citrulline (micromolar). C RATES(14) is d/dt NO3 in component NO3 (micromolar). C RATES(10) is d/dt NOHA in component NOHA (micromolar). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = 0.9 CONSTS(1) = 100.0 STATES(2) = 0.0 STATES(3) = 0.0 STATES(4) = 0.0 CONSTS(2) = 100.0 CONSTS(3) = 6.6 CONSTS(4) = 6.6 CONSTS(5) = 20.8 CONSTS(6) = 39.9 CONSTS(7) = 0.01 CONSTS(8) = 20.8 STATES(5) = 0.0 STATES(6) = 0.0 CONSTS(9) = 6.6 CONSTS(10) = 6.6 STATES(7) = 0.0 CONSTS(11) = 8.5 CONSTS(12) = 215.6 CONSTS(13) = 175.6 STATES(8) = 0.0 CONSTS(14) = 20.8 STATES(9) = 0.0 STATES(10) = 0.0 STATES(11) = 0.0 CONSTS(15) = 8.6 CONSTS(16) = 399.2 CONSTS(17) = 13.2 CONSTS(18) = 13.2 CONSTS(19) = 39.1 CONSTS(20) = 20.8 STATES(12) = 0.0 STATES(13) = 0.0 STATES(14) = 0.0 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RATES(12) = CONSTS(6)*STATES(3) RATES(1) = ( CONSTS(4)*STATES(2)+ CONSTS(6)*STATES(3)+ CONSTS(7)*STATES(4)*CONSTS(2)) - ( CONSTS(3)*CONSTS(1)*STATES(1)+ CONSTS(5)*STATES(1)) RATES(2) = CONSTS(3)*STATES(1)*CONSTS(1) - ( CONSTS(4)*STATES(2)+ CONSTS(8)*STATES(2)) RATES(5) = ( CONSTS(5)*STATES(1)+ CONSTS(9)*STATES(6)) - CONSTS(10)*STATES(5)*CONSTS(1) RATES(6) = ( CONSTS(8)*STATES(2)+ CONSTS(12)*STATES(7)+ CONSTS(10)*STATES(5)*CONSTS(1)) - ( CONSTS(11)*STATES(6)*CONSTS(2)+ CONSTS(9)*STATES(6)) RATES(7) = CONSTS(11)*STATES(6)*CONSTS(2) - ( CONSTS(13)*STATES(7)+ CONSTS(12)*STATES(7)) RATES(8) = CONSTS(13)*STATES(7) - CONSTS(14)*STATES(8) RATES(9) = ( CONSTS(14)*STATES(8)+ CONSTS(16)*STATES(11)+ CONSTS(18)*STATES(5)*STATES(10)) - ( CONSTS(17)*STATES(9)+ CONSTS(15)*STATES(9)*CONSTS(2)) RATES(11) = CONSTS(15)*STATES(9)*CONSTS(2) - ( CONSTS(19)*STATES(11)+ CONSTS(16)*STATES(11)) RATES(3) = CONSTS(19)*STATES(11) - ( CONSTS(6)*STATES(3)+ CONSTS(20)*STATES(3)) RATES(4) = CONSTS(20)*STATES(3) - CONSTS(7)*STATES(4)*CONSTS(2) RATES(13) = CONSTS(19)*STATES(11) RATES(14) = CONSTS(7)*STATES(4)*CONSTS(2) RATES(10) = CONSTS(17)*STATES(9) - CONSTS(18)*STATES(5)*STATES(10) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = RATES(12) RETURN END