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C C There are a total of 40 entries in the algebraic variable array. C There are a total of 11 entries in each of the rate and state variable arrays. C There are a total of 24 entries in the constant variable array. C C C VOI is t in component environment (second). C CONSTS(1) is R in component environment (J_per_K_per_mol). C CONSTS(2) is T in component environment (kelvin). C CONSTS(3) is F in component environment (C_per_mol). C CONSTS(4) is C_m in component environment (fF). C STATES(1) is q_Ca_o in component environment (fmol). C STATES(2) is q_Ca_i in component environment (fmol). C STATES(3) is q_Na_o in component environment (fmol). C STATES(4) is q_Na_i in component environment (fmol). C STATES(5) is q_P1_NCX in component environment (fmol). C STATES(6) is q_P2_NCX in component environment (fmol). C STATES(7) is q_P3_NCX in component environment (fmol). C STATES(8) is q_P4_NCX in component environment (fmol). C STATES(9) is q_P5_NCX in component environment (fmol). C STATES(10) is q_P6_NCX in component environment (fmol). C ALGBRC(30) is v_Ca_o_NCX in component NCX (fmol_per_sec). C ALGBRC(23) is v_Ca_i_NCX in component NCX (fmol_per_sec). C ALGBRC(34) is v_Na_o_NCX in component NCX (fmol_per_sec). C ALGBRC(20) is v_Na_i_NCX in component NCX (fmol_per_sec). C STATES(11) is q_mem in component environment (fC). C ALGBRC(38) is I_mem_NCX in component NCX (fA). C CONSTS(5) is kappa_1_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(6) is kappa_2_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(7) is kappa_3_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(8) is kappa_4_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(9) is kappa_5_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(10) is kappa_6_NCX in component NCX_parameters (fmol_per_sec). C CONSTS(11) is K_1_NCX in component NCX_parameters (per_fmol). C CONSTS(12) is K_2_NCX in component NCX_parameters (per_fmol). C CONSTS(13) is K_3_NCX in component NCX_parameters (per_fmol). C CONSTS(14) is K_4_NCX in component NCX_parameters (per_fmol). C CONSTS(15) is K_5_NCX in component NCX_parameters (per_fmol). C CONSTS(16) is K_6_NCX in component NCX_parameters (per_fmol). C CONSTS(17) is K_Na_i in component NCX_parameters (per_fmol). C CONSTS(18) is K_Ca_i in component NCX_parameters (per_fmol). C CONSTS(19) is K_Na_o in component NCX_parameters (per_fmol). C CONSTS(20) is K_Ca_o in component NCX_parameters (per_fmol). C CONSTS(21) is nNa_o_NCX in component NCX_parameters (dimensionless). C CONSTS(22) is nNa_i_NCX in component NCX_parameters (dimensionless). C CONSTS(23) is zf_NCX in component NCX_parameters (dimensionless). C CONSTS(24) is zr_NCX in component NCX_parameters (dimensionless). C ALGBRC(2) is mu_Ca_o in component NCX (J_per_mol). C ALGBRC(3) is mu_Ca_i in component NCX (J_per_mol). C ALGBRC(4) is mu_Na_o in component NCX (J_per_mol). C ALGBRC(5) is mu_Na_i in component NCX (J_per_mol). C ALGBRC(6) is mu_P1_NCX in component NCX (J_per_mol). C ALGBRC(7) is mu_P2_NCX in component NCX (J_per_mol). C ALGBRC(8) is mu_P3_NCX in component NCX (J_per_mol). C ALGBRC(9) is mu_P4_NCX in component NCX (J_per_mol). C ALGBRC(10) is mu_P5_NCX in component NCX (J_per_mol). C ALGBRC(11) is mu_P6_NCX in component NCX (J_per_mol). C ALGBRC(39) is v_P1_NCX in component NCX (fmol_per_sec). C ALGBRC(24) is v_P2_NCX in component NCX (fmol_per_sec). C ALGBRC(27) is v_P3_NCX in component NCX (fmol_per_sec). C ALGBRC(31) is v_P4_NCX in component NCX (fmol_per_sec). C ALGBRC(36) is v_P5_NCX in component NCX (fmol_per_sec). C ALGBRC(40) is v_P6_NCX in component NCX (fmol_per_sec). C ALGBRC(12) is Af_r1 in component NCX (J_per_mol). C ALGBRC(18) is Ar_r1 in component NCX (J_per_mol). C ALGBRC(19) is v_r1 in component NCX (fmol_per_sec). C ALGBRC(13) is Af_r2 in component NCX (J_per_mol). C ALGBRC(21) is Ar_r2 in component NCX (J_per_mol). C ALGBRC(22) is v_r2 in component NCX (fmol_per_sec). C ALGBRC(14) is Af_r3 in component NCX (J_per_mol). C ALGBRC(25) is Ar_r3 in component NCX (J_per_mol). C ALGBRC(26) is v_r3 in component NCX (fmol_per_sec). C ALGBRC(15) is Af_r4 in component NCX (J_per_mol). C ALGBRC(28) is Ar_r4 in component NCX (J_per_mol). C ALGBRC(29) is v_r4 in component NCX (fmol_per_sec). C ALGBRC(16) is Af_r5 in component NCX (J_per_mol). C ALGBRC(32) is Ar_r5 in component NCX (J_per_mol). C ALGBRC(33) is v_r5 in component NCX (fmol_per_sec). C ALGBRC(17) is Af_r6 in component NCX (J_per_mol). C ALGBRC(35) is Ar_r6 in component NCX (J_per_mol). C ALGBRC(37) is v_r6 in component NCX (fmol_per_sec). C ALGBRC(1) is V_mem in component NCX (volt). C RATES(1) is d/dt q_Ca_o in component environment (fmol). C RATES(2) is d/dt q_Ca_i in component environment (fmol). C RATES(3) is d/dt q_Na_o in component environment (fmol). C RATES(4) is d/dt q_Na_i in component environment (fmol). C RATES(11) is d/dt q_mem in component environment (fC). C RATES(5) is d/dt q_P1_NCX in component environment (fmol). C RATES(6) is d/dt q_P2_NCX in component environment (fmol). C RATES(7) is d/dt q_P3_NCX in component environment (fmol). C RATES(8) is d/dt q_P4_NCX in component environment (fmol). C RATES(9) is d/dt q_P5_NCX in component environment (fmol). C RATES(10) is d/dt q_P6_NCX in component environment (fmol). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 8.314 CONSTS(2) = 310 CONSTS(3) = 96485 CONSTS(4) = 153400 STATES(1) = 9.3276 STATES(2) = 0.00456 STATES(3) = 725.48 STATES(4) = 380 STATES(5) = 0.000103509 STATES(6) = 0.000103509 STATES(7) = 0.000103509 STATES(8) = 0.000103509 STATES(9) = 0.000103509 STATES(10) = 0.000103509 STATES(11) = -13039 CONSTS(5) = 417309 CONSTS(6) = 1.39522e+07 CONSTS(7) = 472.755 CONSTS(8) = 1.39522e+07 CONSTS(9) = 417309 CONSTS(10) = 0.370405 CONSTS(11) = 2.93394e+08 CONSTS(12) = 14.1045 CONSTS(13) = 263471 CONSTS(14) = 2.39875e+06 CONSTS(15) = 2373.73 CONSTS(16) = 956.214 CONSTS(17) = 0.0137751 CONSTS(18) = 10.2446 CONSTS(19) = 0.470129 CONSTS(20) = 7572.91 CONSTS(21) = 3 CONSTS(22) = 3 CONSTS(23) = -0.55679 CONSTS(24) = 0.44321 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(6) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(5)) ALGBRC(12) = ALGBRC(6) ALGBRC(5) = CONSTS(1)*CONSTS(2)*log( CONSTS(17)*STATES(4)) ALGBRC(7) = CONSTS(1)*CONSTS(2)*log( CONSTS(12)*STATES(6)) ALGBRC(18) = CONSTS(22)*ALGBRC(5)+ALGBRC(7) ALGBRC(19) = CONSTS(5)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(18)/( CONSTS(1)*CONSTS(2)))) ALGBRC(20) = CONSTS(22)*ALGBRC(19) RATES(4) = ALGBRC(20) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(18)*STATES(2)) ALGBRC(13) = ALGBRC(7)+ALGBRC(3) ALGBRC(8) = CONSTS(1)*CONSTS(2)*log( CONSTS(13)*STATES(7)) ALGBRC(21) = ALGBRC(8) ALGBRC(22) = CONSTS(6)*(EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(21)/( CONSTS(1)*CONSTS(2)))) ALGBRC(23) = - ALGBRC(22) RATES(2) = ALGBRC(23) ALGBRC(24) = ALGBRC(19) - ALGBRC(22) RATES(6) = ALGBRC(24) ALGBRC(14) = ALGBRC(8) ALGBRC(9) = CONSTS(1)*CONSTS(2)*log( CONSTS(14)*STATES(8)) ALGBRC(25) = ALGBRC(9) ALGBRC(26) = CONSTS(7)*(EXP(ALGBRC(14)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(25)/( CONSTS(1)*CONSTS(2)))) ALGBRC(27) = ALGBRC(22) - ALGBRC(26) RATES(7) = ALGBRC(27) ALGBRC(15) = ALGBRC(9) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(20)*STATES(1)) ALGBRC(10) = CONSTS(1)*CONSTS(2)*log( CONSTS(15)*STATES(9)) ALGBRC(28) = ALGBRC(10)+ALGBRC(2) ALGBRC(29) = CONSTS(8)*(EXP(ALGBRC(15)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(28)/( CONSTS(1)*CONSTS(2)))) ALGBRC(30) = ALGBRC(29) RATES(1) = ALGBRC(30) ALGBRC(31) = - ALGBRC(29)+ALGBRC(26) RATES(8) = ALGBRC(31) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(19)*STATES(3)) ALGBRC(16) = ALGBRC(10)+ CONSTS(21)*ALGBRC(4) ALGBRC(11) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(10)) ALGBRC(32) = ALGBRC(11) ALGBRC(33) = CONSTS(9)*(EXP(ALGBRC(16)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(32)/( CONSTS(1)*CONSTS(2)))) ALGBRC(34) = - CONSTS(21)*ALGBRC(33) RATES(3) = ALGBRC(34) ALGBRC(36) = - ALGBRC(33)+ALGBRC(29) RATES(9) = ALGBRC(36) ALGBRC(1) = STATES(11)/CONSTS(4) ALGBRC(17) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(10))+ CONSTS(23)*CONSTS(3)*ALGBRC(1) ALGBRC(35) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(5))+ CONSTS(24)*CONSTS(3)*ALGBRC(1) ALGBRC(37) = CONSTS(10)*(EXP(ALGBRC(17)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(35)/( CONSTS(1)*CONSTS(2)))) ALGBRC(38) = CONSTS(3)*( - CONSTS(23)*ALGBRC(37)+ CONSTS(24)*ALGBRC(37)) RATES(11) = ALGBRC(38) ALGBRC(39) = ALGBRC(37) - ALGBRC(19) RATES(5) = ALGBRC(39) ALGBRC(40) = - ALGBRC(37)+ALGBRC(33) RATES(10) = ALGBRC(40) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(6) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(5)) ALGBRC(12) = ALGBRC(6) ALGBRC(5) = CONSTS(1)*CONSTS(2)*log( CONSTS(17)*STATES(4)) ALGBRC(7) = CONSTS(1)*CONSTS(2)*log( CONSTS(12)*STATES(6)) ALGBRC(18) = CONSTS(22)*ALGBRC(5)+ALGBRC(7) ALGBRC(19) = CONSTS(5)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(18)/( CONSTS(1)*CONSTS(2)))) ALGBRC(20) = CONSTS(22)*ALGBRC(19) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(18)*STATES(2)) ALGBRC(13) = ALGBRC(7)+ALGBRC(3) ALGBRC(8) = CONSTS(1)*CONSTS(2)*log( CONSTS(13)*STATES(7)) ALGBRC(21) = ALGBRC(8) ALGBRC(22) = CONSTS(6)*(EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(21)/( CONSTS(1)*CONSTS(2)))) ALGBRC(23) = - ALGBRC(22) ALGBRC(24) = ALGBRC(19) - ALGBRC(22) ALGBRC(14) = ALGBRC(8) ALGBRC(9) = CONSTS(1)*CONSTS(2)*log( CONSTS(14)*STATES(8)) ALGBRC(25) = ALGBRC(9) ALGBRC(26) = CONSTS(7)*(EXP(ALGBRC(14)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(25)/( CONSTS(1)*CONSTS(2)))) ALGBRC(27) = ALGBRC(22) - ALGBRC(26) ALGBRC(15) = ALGBRC(9) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(20)*STATES(1)) ALGBRC(10) = CONSTS(1)*CONSTS(2)*log( CONSTS(15)*STATES(9)) ALGBRC(28) = ALGBRC(10)+ALGBRC(2) ALGBRC(29) = CONSTS(8)*(EXP(ALGBRC(15)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(28)/( CONSTS(1)*CONSTS(2)))) ALGBRC(30) = ALGBRC(29) ALGBRC(31) = - ALGBRC(29)+ALGBRC(26) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(19)*STATES(3)) ALGBRC(16) = ALGBRC(10)+ CONSTS(21)*ALGBRC(4) ALGBRC(11) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(10)) ALGBRC(32) = ALGBRC(11) ALGBRC(33) = CONSTS(9)*(EXP(ALGBRC(16)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(32)/( CONSTS(1)*CONSTS(2)))) ALGBRC(34) = - CONSTS(21)*ALGBRC(33) ALGBRC(36) = - ALGBRC(33)+ALGBRC(29) ALGBRC(1) = STATES(11)/CONSTS(4) ALGBRC(17) = CONSTS(1)*CONSTS(2)*log( CONSTS(16)*STATES(10))+ CONSTS(23)*CONSTS(3)*ALGBRC(1) ALGBRC(35) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(5))+ CONSTS(24)*CONSTS(3)*ALGBRC(1) ALGBRC(37) = CONSTS(10)*(EXP(ALGBRC(17)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(35)/( CONSTS(1)*CONSTS(2)))) ALGBRC(38) = CONSTS(3)*( - CONSTS(23)*ALGBRC(37)+ CONSTS(24)*ALGBRC(37)) ALGBRC(39) = ALGBRC(37) - ALGBRC(19) ALGBRC(40) = - ALGBRC(37)+ALGBRC(33) RETURN END