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C C There are a total of 22 entries in the algebraic variable array. C There are a total of 4 entries in each of the rate and state variable arrays. C There are a total of 26 entries in the constant variable array. C C C VOI is t in component GLUT2_BG (second). C CONSTS(1) is R in component params_BG (J_per_K_mol). C CONSTS(2) is T in component params_BG (kelvin). C CONSTS(3) is K_Ai in component params_BG (per_fmol). C CONSTS(24) is q_init_Ai in component params_BG (fmol). C CONSTS(4) is K_Ao in component params_BG (per_fmol). C CONSTS(21) is q_init_Ao in component params_BG (fmol). C CONSTS(5) is K_1 in component params_BG (per_fmol). C CONSTS(6) is q_init_1 in component params_BG (fmol). C CONSTS(7) is K_2 in component params_BG (per_fmol). C CONSTS(8) is q_init_2 in component params_BG (fmol). C CONSTS(9) is K_3 in component params_BG (per_fmol). C CONSTS(10) is q_init_3 in component params_BG (fmol). C CONSTS(11) is K_4 in component params_BG (per_fmol). C CONSTS(12) is q_init_4 in component params_BG (fmol). C CONSTS(13) is kappa_r1 in component params_BG (fmol_per_s). C CONSTS(14) is kappa_r2 in component params_BG (fmol_per_s). C CONSTS(15) is kappa_r3 in component params_BG (fmol_per_s). C CONSTS(16) is kappa_r4 in component params_BG (fmol_per_s). C CONSTS(26) is mu_Ai in component GLUT2_BG (J_per_mol). C ALGBRC(17) is v_Ai in component GLUT2_BG (fmol_per_s). C CONSTS(23) is mu_Ao in component GLUT2_BG (J_per_mol). C ALGBRC(18) is v_Ao in component GLUT2_BG (fmol_per_s). C ALGBRC(1) is mu_1 in component GLUT2_BG (J_per_mol). C ALGBRC(19) is v_1 in component GLUT2_BG (fmol_per_s). C ALGBRC(2) is mu_2 in component GLUT2_BG (J_per_mol). C ALGBRC(20) is v_2 in component GLUT2_BG (fmol_per_s). C ALGBRC(3) is mu_3 in component GLUT2_BG (J_per_mol). C ALGBRC(21) is v_3 in component GLUT2_BG (fmol_per_s). C ALGBRC(4) is mu_4 in component GLUT2_BG (J_per_mol). C ALGBRC(22) is v_4 in component GLUT2_BG (fmol_per_s). C ALGBRC(5) is A_f_r1 in component GLUT2_BG (J_per_mol). C ALGBRC(7) is v_r1 in component GLUT2_BG (fmol_per_s). C ALGBRC(6) is A_r_r1 in component GLUT2_BG (J_per_mol). C ALGBRC(8) is A_f_r2 in component GLUT2_BG (J_per_mol). C ALGBRC(10) is v_r2 in component GLUT2_BG (fmol_per_s). C ALGBRC(9) is A_r_r2 in component GLUT2_BG (J_per_mol). C ALGBRC(11) is A_f_r3 in component GLUT2_BG (J_per_mol). C ALGBRC(15) is v_r3 in component GLUT2_BG (fmol_per_s). C ALGBRC(13) is A_r_r3 in component GLUT2_BG (J_per_mol). C ALGBRC(12) is A_f_r4 in component GLUT2_BG (J_per_mol). C ALGBRC(16) is v_r4 in component GLUT2_BG (fmol_per_s). C ALGBRC(14) is A_r_r4 in component GLUT2_BG (J_per_mol). C CONSTS(25) is q_Ai in component GLUT2_BG (fmol). C CONSTS(22) is q_Ao in component GLUT2_BG (fmol). C STATES(1) is q_1 in component GLUT2_BG (fmol). C STATES(2) is q_2 in component GLUT2_BG (fmol). C STATES(3) is q_3 in component GLUT2_BG (fmol). C STATES(4) is q_4 in component GLUT2_BG (fmol). C CONSTS(17) is V_i in component params_BG (pL). C CONSTS(18) is g_i in component params_BG (mM). C CONSTS(19) is g_o in component params_BG (mM). C CONSTS(20) is V_o in component params_BG (pL). C RATES(1) is d/dt q_1 in component GLUT2_BG (fmol). C RATES(2) is d/dt q_2 in component GLUT2_BG (fmol). C RATES(3) is d/dt q_3 in component GLUT2_BG (fmol). C RATES(4) is d/dt q_4 in component GLUT2_BG (fmol). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 8.31 CONSTS(2) = 273.15 CONSTS(3) = 149.65 CONSTS(4) = 149.65 CONSTS(5) = 33.20 CONSTS(6) = 0.0017 CONSTS(7) = 4.25e+03 CONSTS(8) = 0.0017 CONSTS(9) = 344.59 CONSTS(10) = 0.0017 CONSTS(11) = 1.99 CONSTS(12) = 0.0017 CONSTS(13) = 0.36 CONSTS(14) = 0.26 CONSTS(15) = 1.01e+05 CONSTS(16) = 1.01e+04 CONSTS(17) = 0.09 CONSTS(18) = 10 CONSTS(19) = 1e-5 CONSTS(20) = 0.09 CONSTS(21) = CONSTS(19)*CONSTS(20) CONSTS(22) = CONSTS(21) CONSTS(23) = CONSTS(1)*CONSTS(2)*log( CONSTS(4)*CONSTS(22)) CONSTS(24) = CONSTS(18)*CONSTS(17) CONSTS(25) = CONSTS(24) CONSTS(26) = CONSTS(1)*CONSTS(2)*log( CONSTS(3)*CONSTS(25)) STATES(1) = CONSTS(6) STATES(2) = CONSTS(8) STATES(3) = CONSTS(10) STATES(4) = CONSTS(12) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(4)) ALGBRC(5) = ALGBRC(4) ALGBRC(1) = CONSTS(1)*CONSTS(2)*log( CONSTS(5)*STATES(1)) ALGBRC(6) = ALGBRC(1) ALGBRC(7) = CONSTS(13)*(EXP(ALGBRC(5)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(6)/( CONSTS(1)*CONSTS(2)))) ALGBRC(11) = CONSTS(23)+ALGBRC(1) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(7)*STATES(2)) ALGBRC(13) = ALGBRC(2) ALGBRC(15) = CONSTS(15)*(EXP(ALGBRC(11)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2)))) ALGBRC(19) = ALGBRC(7) - ALGBRC(15) RATES(1) = ALGBRC(19) ALGBRC(8) = ALGBRC(2) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(9)*STATES(3)) ALGBRC(9) = ALGBRC(3) ALGBRC(10) = CONSTS(14)*(EXP(ALGBRC(8)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(9)/( CONSTS(1)*CONSTS(2)))) ALGBRC(20) = ALGBRC(15) - ALGBRC(10) RATES(2) = ALGBRC(20) ALGBRC(12) = ALGBRC(3) ALGBRC(14) = CONSTS(26)+ALGBRC(4) ALGBRC(16) = CONSTS(16)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(14)/( CONSTS(1)*CONSTS(2)))) ALGBRC(21) = ALGBRC(10) - ALGBRC(16) RATES(3) = ALGBRC(21) ALGBRC(22) = ALGBRC(16) - ALGBRC(7) RATES(4) = ALGBRC(22) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(4) = CONSTS(1)*CONSTS(2)*log( CONSTS(11)*STATES(4)) ALGBRC(5) = ALGBRC(4) ALGBRC(1) = CONSTS(1)*CONSTS(2)*log( CONSTS(5)*STATES(1)) ALGBRC(6) = ALGBRC(1) ALGBRC(7) = CONSTS(13)*(EXP(ALGBRC(5)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(6)/( CONSTS(1)*CONSTS(2)))) ALGBRC(11) = CONSTS(23)+ALGBRC(1) ALGBRC(2) = CONSTS(1)*CONSTS(2)*log( CONSTS(7)*STATES(2)) ALGBRC(13) = ALGBRC(2) ALGBRC(15) = CONSTS(15)*(EXP(ALGBRC(11)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(13)/( CONSTS(1)*CONSTS(2)))) ALGBRC(19) = ALGBRC(7) - ALGBRC(15) ALGBRC(8) = ALGBRC(2) ALGBRC(3) = CONSTS(1)*CONSTS(2)*log( CONSTS(9)*STATES(3)) ALGBRC(9) = ALGBRC(3) ALGBRC(10) = CONSTS(14)*(EXP(ALGBRC(8)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(9)/( CONSTS(1)*CONSTS(2)))) ALGBRC(20) = ALGBRC(15) - ALGBRC(10) ALGBRC(12) = ALGBRC(3) ALGBRC(14) = CONSTS(26)+ALGBRC(4) ALGBRC(16) = CONSTS(16)*(EXP(ALGBRC(12)/( CONSTS(1)*CONSTS(2))) - EXP(ALGBRC(14)/( CONSTS(1)*CONSTS(2)))) ALGBRC(21) = ALGBRC(10) - ALGBRC(16) ALGBRC(22) = ALGBRC(16) - ALGBRC(7) ALGBRC(17) = ALGBRC(16) ALGBRC(18) = - ALGBRC(15) RETURN END