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C C There are a total of 10 entries in the algebraic variable array. C There are a total of 7 entries in each of the rate and state variable arrays. C There are a total of 13 entries in the constant variable array. C C C VOI is time in component environment (second). C STATES(1) is q_L in component environment (fmol). C STATES(2) is q_K1 in component environment (fmol). C STATES(3) is q_K2 in component environment (fmol). C STATES(4) is q_LK1 in component environment (fmol). C STATES(5) is q_K2P in component environment (fmol). C STATES(6) is q_P in component environment (fmol). C STATES(7) is q_LK1K2 in component environment (fmol). C ALGBRC(8) is v_Re1 in component RTK (fmol_per_sec). C ALGBRC(9) is v_Re2 in component RTK (fmol_per_sec). C ALGBRC(10) is v_Re3 in component RTK (fmol_per_sec). C CONSTS(1) is kappa_Re1 in component RTK_parameters (fmol_per_sec). C CONSTS(2) is kappa_Re2 in component RTK_parameters (fmol_per_sec). C CONSTS(3) is kappa_Re3 in component RTK_parameters (fmol_per_sec). C CONSTS(4) is K_L in component RTK_parameters (per_fmol). C CONSTS(5) is K_K1 in component RTK_parameters (per_fmol). C CONSTS(6) is K_K2 in component RTK_parameters (per_fmol). C CONSTS(7) is K_LK1 in component RTK_parameters (per_fmol). C CONSTS(8) is K_K2P in component RTK_parameters (per_fmol). C CONSTS(9) is K_P in component RTK_parameters (per_fmol). C CONSTS(10) is K_LK1K2 in component RTK_parameters (per_fmol). C CONSTS(11) is R in component constants (J_per_K_per_mol). C CONSTS(12) is T in component constants (kelvin). C ALGBRC(1) is mu_L in component RTK (J_per_mol). C ALGBRC(2) is mu_K1 in component RTK (J_per_mol). C ALGBRC(3) is mu_K2 in component RTK (J_per_mol). C ALGBRC(4) is mu_LK1 in component RTK (J_per_mol). C ALGBRC(5) is mu_K2P in component RTK (J_per_mol). C ALGBRC(6) is mu_P in component RTK (J_per_mol). C ALGBRC(7) is mu_LK1K2 in component RTK (J_per_mol). C CONSTS(13) is F in component constants (C_per_mol). C RATES(1) is d/dt q_L in component environment (fmol). C RATES(2) is d/dt q_K1 in component environment (fmol). C RATES(3) is d/dt q_K2 in component environment (fmol). C RATES(4) is d/dt q_LK1 in component environment (fmol). C RATES(5) is d/dt q_K2P in component environment (fmol). C RATES(6) is d/dt q_P in component environment (fmol). C RATES(7) is d/dt q_LK1K2 in component environment (fmol). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = 1 STATES(2) = 1e-3 STATES(3) = 1e-3 STATES(4) = 1e-6 STATES(5) = 1e-9 STATES(6) = 1 STATES(7) = 1e-9 CONSTS(1) = 0.000186898 CONSTS(2) = 0.0125535 CONSTS(3) = 132.879 CONSTS(4) = 197.162 CONSTS(5) = 197.162 CONSTS(6) = 4.01297e+09 CONSTS(7) = 0.00144219 CONSTS(8) = 3.79118e-07 CONSTS(9) = 2.54645e+07 CONSTS(10) = 2.14714e-05 CONSTS(11) = 8.31 CONSTS(12) = 310 CONSTS(13) = 96485 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = CONSTS(11)*CONSTS(12)*log( CONSTS(4)*STATES(1)) ALGBRC(2) = CONSTS(11)*CONSTS(12)*log( CONSTS(5)*STATES(2)) ALGBRC(4) = CONSTS(11)*CONSTS(12)*log( CONSTS(7)*STATES(4)) ALGBRC(8) = CONSTS(1)*(EXP((ALGBRC(1)+ALGBRC(2))/( CONSTS(11)*CONSTS(12))) - EXP(ALGBRC(4)/( CONSTS(11)*CONSTS(12)))) RATES(1) = - ALGBRC(8) RATES(2) = - ALGBRC(8) ALGBRC(3) = CONSTS(11)*CONSTS(12)*log( CONSTS(6)*STATES(3)) ALGBRC(7) = CONSTS(11)*CONSTS(12)*log( CONSTS(10)*STATES(7)) ALGBRC(9) = CONSTS(2)*(EXP((ALGBRC(4)+ALGBRC(3))/( CONSTS(11)*CONSTS(12))) - EXP(ALGBRC(7)/( CONSTS(11)*CONSTS(12)))) RATES(3) = - ALGBRC(9) ALGBRC(5) = CONSTS(11)*CONSTS(12)*log( CONSTS(8)*STATES(5)) ALGBRC(6) = CONSTS(11)*CONSTS(12)*log( CONSTS(9)*STATES(6)) ALGBRC(10) = CONSTS(3)*(EXP((ALGBRC(6)+ALGBRC(7))/( CONSTS(11)*CONSTS(12))) - EXP((ALGBRC(4)+ALGBRC(5))/( CONSTS(11)*CONSTS(12)))) RATES(4) = (ALGBRC(8) - ALGBRC(9))+ALGBRC(10) RATES(5) = ALGBRC(10) RATES(6) = - ALGBRC(10) RATES(7) = ALGBRC(9) - ALGBRC(10) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = CONSTS(11)*CONSTS(12)*log( CONSTS(4)*STATES(1)) ALGBRC(2) = CONSTS(11)*CONSTS(12)*log( CONSTS(5)*STATES(2)) ALGBRC(4) = CONSTS(11)*CONSTS(12)*log( CONSTS(7)*STATES(4)) ALGBRC(8) = CONSTS(1)*(EXP((ALGBRC(1)+ALGBRC(2))/( CONSTS(11)*CONSTS(12))) - EXP(ALGBRC(4)/( CONSTS(11)*CONSTS(12)))) ALGBRC(3) = CONSTS(11)*CONSTS(12)*log( CONSTS(6)*STATES(3)) ALGBRC(7) = CONSTS(11)*CONSTS(12)*log( CONSTS(10)*STATES(7)) ALGBRC(9) = CONSTS(2)*(EXP((ALGBRC(4)+ALGBRC(3))/( CONSTS(11)*CONSTS(12))) - EXP(ALGBRC(7)/( CONSTS(11)*CONSTS(12)))) ALGBRC(5) = CONSTS(11)*CONSTS(12)*log( CONSTS(8)*STATES(5)) ALGBRC(6) = CONSTS(11)*CONSTS(12)*log( CONSTS(9)*STATES(6)) ALGBRC(10) = CONSTS(3)*(EXP((ALGBRC(6)+ALGBRC(7))/( CONSTS(11)*CONSTS(12))) - EXP((ALGBRC(4)+ALGBRC(5))/( CONSTS(11)*CONSTS(12)))) RETURN END