Mathematical modeling of calcium homeostasis in yeast cells

> <apply> <diff> time m > <apply> <times> kM_plus > <ci>CaMtotal<ci> m > <ci>x<ci> 3.0 > <ci>kM_minus<ci> m > <ci>dmdt<ci> > <apply> <times> kM_plus > <ci>CaMtotal<ci> m > <ci>x<ci> 3 > <ci>kM_minus<ci> m > <apply> <diff> time z > <apply> <times> kN_plus > <ci>CaNtotal<ci> z m > <ci>kN_minus<ci> z > <ci>dzdt<ci> > <apply> <times> kN_plus > <ci>CaNtotal<ci> z m > <ci>kN_minus<ci> z > <apply> <diff> time h > <apply> <times> > <apply> <times> d phi 1.0 z > <cn cellml:units="dimensionless">1.0<cn> h > <ci>f<ci> > <cn cellml:units="dimensionless">1.0<cn> > <apply> <times> phi 1.0 z h > <ci>phi<ci> > <cn cellml:units="dimensionless">1.0<cn> > <cn cellml:units="dimensionless">1.0<cn> > <apply> <times> L0 > <apply> <power> > <ci>lamda<ci> y > <ci>N<ci> 1.0 1.0 > <apply> <times> > <apply> <times> lamda y 1.0 > <ci>y<ci> 1.0 > <apply> <power> y > <ci>N<ci> 1.0 1.0 > <ci>psi<ci> > <apply> <plus> 1.0 L0 > <apply> <divide> > <apply> <power> y > <ci>N<ci> 1.0 1.0 > <ci>y<ci> 1.0 > <apply> <times> L0 > <apply> <power> > <ci>lamda<ci> y > <ci>N<ci> 1.0 1.0 > <apply> <times> lamda y 1.0 > <apply> <diff> time x > <apply> <divide> > <ci>Vx<ci> Caex > <ci>Kx<ci> Caex > <apply> <divide> > <apply> <divide> > <ci>h<ci> psi 1.0 z V2 x > <ci>K2<ci> x > <apply> <times> > <cn cellml:units="micromolar">1.0<cn> > <cn cellml:units="micromolar">1.0<cn> > <ci>kc<ci> z V3 x > <ci>K3<ci> x > <ci>alpha<ci> x > <ci>dxdt<ci> > <apply> <divide> > <ci>Vx<ci> Caex > <ci>Kx<ci> Caex > <apply> <divide> > <apply> <divide> > <ci>h<ci> psi 1 z V1 x > <ci>K1<ci> x > <apply> <times> > <apply> <times> h psi 1 z V2 x > <ci>K2<ci> x > <apply> <times> > <cn cellml:units="micromolar">1<cn> > <cn cellml:units="micromolar">1<cn> > <ci>kc<ci> z V3 x > <ci>K3<ci> x > <ci>alpha<ci> x > <ci>L0<ci> > <cn cellml:units="dimensionless">10.0<cn> > <apply> <minus> N 2.0 > <ci>y<ci> > <cn cellml:units="micromolar">1.0<cn> z gene expression calcium homeostasis calcium dynamics yeast 16445978 The University of Auckland, Auckland Bioengineering Institute 2007-09-07T14:34:45+12:00 4 2007-05-26T00:00:00+00:00 The model has now been fixed such that it runs in PCEnv and COR and can recreate the published results. Units have been checked and are all correct and are consistent. James Lawson Richard Catherine Lloyd 2006-04-00 00:00 Cui and Kaandorp's 2006 mathematical model of calcium homeostasis in yeast cells. Catherine Lloyd May c.lloyd@auckland.ac.nz James Lawson Richard 2009-06-08T15:34:20+12:00 Jiangjun Cui Mathematical modeling of calcium homeostasis in yeast cells 39 337 348 Some extra equations have been added to define differential expressions as variables to allow them to be graphed. No changes to the guts of the model have been made. The model has now been fixed such that it runs in PCEnv and COR and can recreate the published results. Units have been checked and are all correct and are consistent. Jaap Kaandorp A 2007-09-01T16:31:11+12:00 Cell Calcium The University of Auckland Auckland Bioengineering Institute Catherine Lloyd May This is the CellML description of Cui and Kaandorp's 2006 mathematical model of calcium homeostasis in yeast cells. Catherine Lloyd keyword Ca-bound calmodulin m nuclear fraction of Crz1p h updated curation status, removed reference link from documentation activated calcineurin z cytosolic calcium x