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# Size of variable arrays: sizeAlgebraic = 2 sizeStates = 2 sizeConstants = 9 from math import * from numpy import * def createLegends(): legend_states = [""] * sizeStates legend_rates = [""] * sizeStates legend_algebraic = [""] * sizeAlgebraic legend_voi = "" legend_constants = [""] * sizeConstants legend_voi = "time in component environment (second)" legend_states[0] = "a in component a (dimensionless)" legend_algebraic[0] = "ainf in component a (dimensionless)" legend_constants[0] = "w in component a (dimensionless)" legend_constants[1] = "ka in component a (dimensionless)" legend_constants[2] = "th0 in component a (dimensionless)" legend_constants[3] = "n in component a (dimensionless)" legend_constants[4] = "wi in component a (dimensionless)" legend_constants[8] = "noise in component a (dimensionless)" legend_states[1] = "s in component s (dimensionless)" legend_algebraic[1] = "sinf in component s (dimensionless)" legend_constants[5] = "taus in component s (second)" legend_constants[6] = "ks in component s (dimensionless)" legend_constants[7] = "ths in component s (dimensionless)" legend_rates[0] = "d/dt a in component a (dimensionless)" legend_rates[1] = "d/dt s in component s (dimensionless)" return (legend_states, legend_algebraic, legend_voi, legend_constants) def initConsts(): constants = [0.0] * sizeConstants; states = [0.0] * sizeStates; states[0] = 0.1 constants[0] = 0.8 constants[1] = -0.05 constants[2] = 0.17 constants[3] = 0.01 constants[4] = 0 states[1] = 0.3 constants[5] = 250 constants[6] = 0.05 constants[7] = 0.2 constants[8] = constants[3]*constants[4] return (states, constants) def computeRates(voi, states, constants): rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic algebraic[0] = 1.00000/(1.00000+exp((constants[0]*states[1]*states[0]-constants[2])/constants[1])) rates[0] = ((algebraic[0]-states[0])+constants[8])/1.00000 algebraic[1] = 1.00000/(1.00000+exp((states[0]-constants[7])/constants[6])) rates[1] = (algebraic[1]-states[1])/constants[5] return(rates) def computeAlgebraic(constants, states, voi): algebraic = array([[0.0] * len(voi)] * sizeAlgebraic) states = array(states) voi = array(voi) algebraic[0] = 1.00000/(1.00000+exp((constants[0]*states[1]*states[0]-constants[2])/constants[1])) algebraic[1] = 1.00000/(1.00000+exp((states[0]-constants[7])/constants[6])) return algebraic def solve_model(): """Solve model with ODE solver""" from scipy.integrate import ode # Initialise constants and state variables (init_states, constants) = initConsts() # Set timespan to solve over voi = linspace(0, 10, 500) # Construct ODE object to solve r = ode(computeRates) r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1) r.set_initial_value(init_states, voi[0]) r.set_f_params(constants) # Solve model states = array([[0.0] * len(voi)] * sizeStates) states[:,0] = init_states for (i,t) in enumerate(voi[1:]): if r.successful(): r.integrate(t) states[:,i+1] = r.y else: break # Compute algebraic variables algebraic = computeAlgebraic(constants, states, voi) return (voi, states, algebraic) def plot_model(voi, states, algebraic): """Plot variables against variable of integration""" import pylab (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends() pylab.figure(1) pylab.plot(voi,vstack((states,algebraic)).T) pylab.xlabel(legend_voi) pylab.legend(legend_states + legend_algebraic, loc='best') pylab.show() if __name__ == "__main__": (voi, states, algebraic) = solve_model() plot_model(voi, states, algebraic)