Generated Code
The following is c code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 85 entries in the algebraic variable array.
There are a total of 18 entries in each of the rate and state variable arrays.
There are a total of 71 entries in the constant variable array.
*/
/*
* VOI is time in component environment (ms).
* STATES[0] is V in component membrane (mV).
* CONSTANTS[0] is R in component membrane (millijoule_per_mole_kelvin).
* CONSTANTS[1] is T in component membrane (kelvin).
* CONSTANTS[2] is F in component membrane (coulomb_per_mole).
* CONSTANTS[3] is Cm in component membrane (uF).
* ALGEBRAIC[22] is i_Na in component sodium_current (uA).
* ALGEBRAIC[24] is i_t in component Ca_independent_transient_outward_K_current (uA).
* ALGEBRAIC[25] is i_ss in component steady_state_outward_K_current (uA).
* ALGEBRAIC[26] is i_K1 in component inward_rectifier (uA).
* ALGEBRAIC[29] is i_f in component hyperpolarisation_activated_current (uA).
* ALGEBRAIC[30] is i_B_Na in component background_currents (uA).
* ALGEBRAIC[31] is i_B_K in component background_currents (uA).
* ALGEBRAIC[34] is i_NaK in component sodium_potassium_pump (uA).
* ALGEBRAIC[75] is i_Ncx2 in component Na_Ca_Exchanger (uA).
* ALGEBRAIC[78] is i_pCa2 in component SarcolemMal_Ca_pump (uA).
* ALGEBRAIC[72] is i_LCC2 in component LCC_current (uA).
* ALGEBRAIC[81] is i_CaB2 in component Background_Ca_current (uA).
* ALGEBRAIC[20] is i_Stim in component membrane (uA).
* CONSTANTS[4] is stim_period in component membrane (ms).
* CONSTANTS[5] is stim_duration in component membrane (ms).
* CONSTANTS[6] is stim_amplitude in component membrane (uA).
* ALGEBRAIC[0] is FVRT in component membrane (dimensionless).
* ALGEBRAIC[19] is FVRT_Ca in component membrane (dimensionless).
* CONSTANTS[7] is Vmyo in component cell_geometry (um3).
* CONSTANTS[8] is Vmyo_uL in component cell_geometry (uL).
* CONSTANTS[9] is VSR_uL in component cell_geometry (uL).
* ALGEBRAIC[21] is E_Na in component sodium_current (mV).
* CONSTANTS[10] is g_Na in component sodium_current (mSi).
* STATES[1] is Na_i in component intracellular_ion_concentrations (mM).
* CONSTANTS[11] is Na_o in component extracellular_ion_concentrations (mM).
* STATES[2] is m in component sodium_current_m_gate (dimensionless).
* STATES[3] is h in component sodium_current_h_gate (dimensionless).
* STATES[4] is j in component sodium_current_j_gate (dimensionless).
* ALGEBRAIC[1] is m_infinity in component sodium_current_m_gate (dimensionless).
* ALGEBRAIC[11] is tau_m in component sodium_current_m_gate (ms).
* ALGEBRAIC[2] is h_infinity in component sodium_current_h_gate (dimensionless).
* ALGEBRAIC[12] is tau_h in component sodium_current_h_gate (ms).
* ALGEBRAIC[3] is j_infinity in component sodium_current_j_gate (dimensionless).
* ALGEBRAIC[13] is tau_j in component sodium_current_j_gate (ms).
* ALGEBRAIC[23] is E_K in component Ca_independent_transient_outward_K_current (mV).
* CONSTANTS[12] is g_t in component Ca_independent_transient_outward_K_current (mSi).
* CONSTANTS[13] is a in component Ca_independent_transient_outward_K_current (dimensionless).
* CONSTANTS[14] is b in component Ca_independent_transient_outward_K_current (dimensionless).
* CONSTANTS[15] is K_o in component extracellular_ion_concentrations (mM).
* STATES[5] is K_i in component intracellular_ion_concentrations (mM).
* STATES[6] is r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* STATES[7] is s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* STATES[8] is s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless).
* ALGEBRAIC[14] is tau_r in component Ca_independent_transient_outward_K_current_r_gate (ms).
* ALGEBRAIC[4] is r_infinity in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* ALGEBRAIC[15] is tau_s in component Ca_independent_transient_outward_K_current_s_gate (ms).
* ALGEBRAIC[5] is s_infinity in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* ALGEBRAIC[16] is tau_s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (ms).
* ALGEBRAIC[6] is s_slow_infinity in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless).
* CONSTANTS[16] is g_ss in component steady_state_outward_K_current (mSi).
* STATES[9] is r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless).
* STATES[10] is s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless).
* ALGEBRAIC[17] is tau_r_ss in component steady_state_outward_K_current_r_ss_gate (ms).
* ALGEBRAIC[7] is r_ss_infinity in component steady_state_outward_K_current_r_ss_gate (dimensionless).
* CONSTANTS[67] is tau_s_ss in component steady_state_outward_K_current_s_ss_gate (ms).
* ALGEBRAIC[8] is s_ss_infinity in component steady_state_outward_K_current_s_ss_gate (dimensionless).
* CONSTANTS[17] is g_K1 in component inward_rectifier (mSi).
* ALGEBRAIC[27] is i_f_Na in component hyperpolarisation_activated_current (uA).
* ALGEBRAIC[28] is i_f_K in component hyperpolarisation_activated_current (uA).
* CONSTANTS[18] is g_f in component hyperpolarisation_activated_current (mSi).
* CONSTANTS[19] is f_Na in component hyperpolarisation_activated_current (dimensionless).
* CONSTANTS[68] is f_K in component hyperpolarisation_activated_current (dimensionless).
* STATES[11] is y in component hyperpolarisation_activated_current_y_gate (dimensionless).
* ALGEBRAIC[18] is tau_y in component hyperpolarisation_activated_current_y_gate (ms).
* ALGEBRAIC[9] is y_infinity in component hyperpolarisation_activated_current_y_gate (dimensionless).
* ALGEBRAIC[32] is i_B in component background_currents (uA).
* CONSTANTS[20] is g_B_Na in component background_currents (mSi).
* CONSTANTS[21] is g_B_K in component background_currents (mSi).
* CONSTANTS[22] is i_NaK_max in component sodium_potassium_pump (uA).
* ALGEBRAIC[33] is nu_1 in component sodium_potassium_pump (dimensionless).
* CONSTANTS[23] is gamma1 in component sodium_potassium_pump (dimensionless).
* CONSTANTS[24] is KdNaio in component sodium_potassium_pump (mM).
* CONSTANTS[25] is KdNais in component sodium_potassium_pump (mM).
* CONSTANTS[26] is KdNaes in component sodium_potassium_pump (mM).
* CONSTANTS[27] is Delta in component sodium_potassium_pump (dimensionless).
* CONSTANTS[28] is alpha in component sodium_potassium_pump (mM).
* CONSTANTS[29] is Ca_o in component extracellular_ion_concentrations (mM).
* CONSTANTS[30] is g_D in component CaRU (um3_per_ms).
* CONSTANTS[31] is J_R in component CaRU (um3_per_ms).
* CONSTANTS[32] is J_L in component CaRU (um3_per_ms).
* CONSTANTS[33] is N in component CaRU (dimensionless).
* STATES[12] is Ca_i in component intracellular_ion_concentrations (mM).
* STATES[13] is Ca_SR in component intracellular_ion_concentrations (mM).
* ALGEBRAIC[64] is i_RyR2 in component RyR_current (mM_per_ms).
* ALGEBRAIC[44] is C_oc in component DS_Calcium_Concentrations (mM).
* ALGEBRAIC[42] is C_co in component DS_Calcium_Concentrations (mM).
* CONSTANTS[34] is V_L in component CaRU_Transitions (mV).
* CONSTANTS[35] is del_VL in component CaRU_Transitions (mV).
* CONSTANTS[36] is phi_L in component CaRU_Transitions (dimensionless).
* CONSTANTS[37] is t_L in component CaRU_Transitions (ms).
* CONSTANTS[38] is tau_L in component CaRU_Transitions (ms).
* CONSTANTS[39] is t_R in component CaRU_Transitions (ms).
* CONSTANTS[40] is tau_R in component CaRU_Transitions (ms).
* CONSTANTS[41] is phi_R in component CaRU_Transitions (dimensionless).
* CONSTANTS[42] is theta_R in component CaRU_Transitions (dimensionless).
* CONSTANTS[43] is K_RyR in component CaRU_Transitions (mM).
* CONSTANTS[44] is K_L in component CaRU_Transitions (mM).
* CONSTANTS[45] is a1 in component CaRU_Transitions (dimensionless).
* CONSTANTS[46] is b1 in component CaRU_Transitions (dimensionless).
* CONSTANTS[47] is c in component CaRU_Transitions (dimensionless).
* CONSTANTS[48] is d in component CaRU_Transitions (dimensionless).
* ALGEBRAIC[35] is expVL in component CaRU_Transitions (dimensionless).
* ALGEBRAIC[36] is alpha_p in component CaRU_Transitions (per_ms).
* CONSTANTS[69] is alpha_m in component CaRU_Transitions (per_ms).
* ALGEBRAIC[45] is beta_poc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[37] is beta_pcc in component CaRU_Transitions (per_ms).
* CONSTANTS[70] is beta_m in component CaRU_Transitions (per_ms).
* ALGEBRAIC[43] is epsilon_pco in component CaRU_Transitions (per_ms).
* ALGEBRAIC[38] is epsilon_pcc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[39] is epsilon_m in component CaRU_Transitions (per_ms).
* ALGEBRAIC[46] is mu_poc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[40] is mu_pcc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[47] is mu_moc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[41] is mu_mcc in component CaRU_Transitions (per_ms).
* ALGEBRAIC[10] is C_cc in component DS_Calcium_Concentrations (mM).
* ALGEBRAIC[51] is J_Loo in component LCC_and_RyR_fluxes (um3_mM_per_ms).
* ALGEBRAIC[50] is J_Loc in component LCC_and_RyR_fluxes (um3_mM_per_ms).
* ALGEBRAIC[48] is J_Rco in component LCC_and_RyR_fluxes (um3_mM_per_ms).
* ALGEBRAIC[49] is J_Roo in component LCC_and_RyR_fluxes (um3_mM_per_ms).
* ALGEBRAIC[52] is denom in component CaRU_states (per_ms3).
* ALGEBRAIC[53] is P1 in component CaRU_states (dimensionless).
* ALGEBRAIC[54] is P2 in component CaRU_states (dimensionless).
* ALGEBRAIC[55] is P3 in component CaRU_states (dimensionless).
* ALGEBRAIC[56] is P4 in component CaRU_states (dimensionless).
* ALGEBRAIC[57] is r_1 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[59] is r_2 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[61] is r_3 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[63] is r_4 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[65] is r_5 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[67] is r_6 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[69] is r_7 in component CaRU_reduced_states (per_ms).
* ALGEBRAIC[71] is r_8 in component CaRU_reduced_states (per_ms).
* STATES[14] is z_1 in component CaRU_reduced_states (dimensionless).
* STATES[15] is z_2 in component CaRU_reduced_states (dimensionless).
* STATES[16] is z_3 in component CaRU_reduced_states (dimensionless).
* ALGEBRAIC[73] is z_4 in component CaRU_reduced_states (dimensionless).
* ALGEBRAIC[58] is J_R1 in component RyR_current (um3_mM_per_ms).
* ALGEBRAIC[60] is J_R3 in component RyR_current (um3_mM_per_ms).
* ALGEBRAIC[62] is i_RyR1 in component RyR_current (mM_per_ms).
* ALGEBRAIC[66] is J_L1 in component LCC_current (um3_mM_per_ms).
* ALGEBRAIC[68] is J_L2 in component LCC_current (um3_mM_per_ms).
* ALGEBRAIC[70] is i_LCC1 in component LCC_current (mM_per_ms).
* CONSTANTS[49] is K_mNa in component Na_Ca_Exchanger (mM).
* CONSTANTS[50] is K_mCa in component Na_Ca_Exchanger (mM).
* CONSTANTS[51] is eta in component Na_Ca_Exchanger (dimensionless).
* CONSTANTS[52] is k_sat in component Na_Ca_Exchanger (dimensionless).
* CONSTANTS[53] is g_NCX in component Na_Ca_Exchanger (mM_per_ms).
* ALGEBRAIC[74] is i_Ncx1 in component Na_Ca_Exchanger (mM_per_ms).
* CONSTANTS[54] is g_SERCA in component SERCA (mM_per_ms).
* CONSTANTS[55] is K_SERCA in component SERCA (mM).
* ALGEBRAIC[76] is i_SERCA in component SERCA (mM_per_ms).
* CONSTANTS[56] is g_pCa in component SarcolemMal_Ca_pump (mM_per_ms).
* CONSTANTS[57] is K_mpCa in component SarcolemMal_Ca_pump (mM).
* ALGEBRAIC[77] is i_pCa1 in component SarcolemMal_Ca_pump (mM_per_ms).
* ALGEBRAIC[79] is E_Ca in component Background_Ca_current (mV).
* CONSTANTS[58] is g_CaB in component Background_Ca_current (mM_per_mV_ms).
* ALGEBRAIC[80] is i_CaB1 in component Background_Ca_current (mM_per_ms).
* CONSTANTS[59] is g_SRl in component SR_Ca_leak_current (per_ms).
* ALGEBRAIC[82] is i_SR in component SR_Ca_leak_current (mM_per_ms).
* CONSTANTS[60] is k_m_TRPN in component troponin_Ca_buffer (per_ms).
* CONSTANTS[61] is k_p_TRPN in component troponin_Ca_buffer (per_mM_ms).
* CONSTANTS[62] is B_TRPN in component troponin_Ca_buffer (mM).
* STATES[17] is TRPN in component intracellular_ion_concentrations (mM).
* ALGEBRAIC[83] is i_TRPN in component troponin_Ca_buffer (mM_per_ms).
* CONSTANTS[63] is k_CMDN in component calmodulin_Ca_buffer (mM).
* CONSTANTS[64] is B_CMDN in component calmodulin_Ca_buffer (mM).
* ALGEBRAIC[84] is beta_CMDN in component calmodulin_Ca_buffer (dimensionless).
* CONSTANTS[65] is EGTA_tot in component calmodulin_Ca_buffer (mM).
* CONSTANTS[66] is KmEGTA in component calmodulin_Ca_buffer (mM).
* RATES[0] is d/dt V in component membrane (mV).
* RATES[2] is d/dt m in component sodium_current_m_gate (dimensionless).
* RATES[3] is d/dt h in component sodium_current_h_gate (dimensionless).
* RATES[4] is d/dt j in component sodium_current_j_gate (dimensionless).
* RATES[6] is d/dt r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless).
* RATES[7] is d/dt s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless).
* RATES[8] is d/dt s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless).
* RATES[9] is d/dt r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless).
* RATES[10] is d/dt s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless).
* RATES[11] is d/dt y in component hyperpolarisation_activated_current_y_gate (dimensionless).
* RATES[14] is d/dt z_1 in component CaRU_reduced_states (dimensionless).
* RATES[15] is d/dt z_2 in component CaRU_reduced_states (dimensionless).
* RATES[16] is d/dt z_3 in component CaRU_reduced_states (dimensionless).
* RATES[1] is d/dt Na_i in component intracellular_ion_concentrations (mM).
* RATES[5] is d/dt K_i in component intracellular_ion_concentrations (mM).
* RATES[17] is d/dt TRPN in component intracellular_ion_concentrations (mM).
* RATES[12] is d/dt Ca_i in component intracellular_ion_concentrations (mM).
* RATES[13] is d/dt Ca_SR in component intracellular_ion_concentrations (mM).
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = -85.1221681609219;
CONSTANTS[0] = 8314;
CONSTANTS[1] = 310;
CONSTANTS[2] = 96487;
CONSTANTS[3] = 0.0001;
CONSTANTS[4] = 1000;
CONSTANTS[5] = 3;
CONSTANTS[6] = -0.0012;
CONSTANTS[7] = 25850;
CONSTANTS[8] = 2.585e-5;
CONSTANTS[9] = 2.098e-6;
CONSTANTS[10] = 0.0007;
STATES[1] = 8.46899983583716;
CONSTANTS[11] = 140;
STATES[2] = 0.00208137744708665;
STATES[3] = 0.815520320018128;
STATES[4] = 0.815471795073686;
CONSTANTS[12] = 2e-5;
CONSTANTS[13] = 0.883;
CONSTANTS[14] = 0.117;
CONSTANTS[15] = 5.4;
STATES[5] = 142.919492013701;
STATES[6] = 0.00146331830465093;
STATES[7] = 0.996934138278418;
STATES[8] = 0.78841193673441;
CONSTANTS[16] = 1.3e-5;
STATES[9] = 0.0019683140031203;
STATES[10] = 0.416987850222633;
CONSTANTS[17] = 4e-5;
CONSTANTS[18] = 1.45e-6;
CONSTANTS[19] = 0.2;
STATES[11] = 0.00566123148325894;
CONSTANTS[20] = 8.015e-8;
CONSTANTS[21] = 1.38e-7;
CONSTANTS[22] = 0.00138;
CONSTANTS[23] = 3.6;
CONSTANTS[24] = 19;
CONSTANTS[25] = 22;
CONSTANTS[26] = 880;
CONSTANTS[27] = 0.3;
CONSTANTS[28] = 1.8;
CONSTANTS[29] = 1.8;
CONSTANTS[30] = 0.1;
CONSTANTS[31] = 0.02;
CONSTANTS[32] = 0.0008;
CONSTANTS[33] = 50000;
STATES[12] = 0.000103020385969363;
STATES[13] = 0.96268028201207;
CONSTANTS[34] = -9;
CONSTANTS[35] = 7;
CONSTANTS[36] = 11.5;
CONSTANTS[37] = 1;
CONSTANTS[38] = 1550;
CONSTANTS[39] = 1.17;
CONSTANTS[40] = 2.4;
CONSTANTS[41] = 0.05;
CONSTANTS[42] = 0.012;
CONSTANTS[43] = 0.065;
CONSTANTS[44] = 0.00038;
CONSTANTS[45] = 0.0625;
CONSTANTS[46] = 14;
CONSTANTS[47] = 0.01;
CONSTANTS[48] = 100;
STATES[14] = 0.990016532916529;
STATES[15] = 0.00845823628523856;
STATES[16] = 0.00151233172289407;
CONSTANTS[49] = 87.5;
CONSTANTS[50] = 1.38;
CONSTANTS[51] = 0.35;
CONSTANTS[52] = 0.1;
CONSTANTS[53] = 0.0234;
CONSTANTS[54] = 0.000235;
CONSTANTS[55] = 0.0004968;
CONSTANTS[56] = 5e-6;
CONSTANTS[57] = 0.00035;
CONSTANTS[58] = 2e-8;
CONSTANTS[59] = 1e-6;
CONSTANTS[60] = 0.04;
CONSTANTS[61] = 40;
CONSTANTS[62] = 0.07;
STATES[17] = 0.0633670056927004;
CONSTANTS[63] = 0.002382;
CONSTANTS[64] = 0.05;
CONSTANTS[65] = 0;
CONSTANTS[66] = 0.00015;
CONSTANTS[67] = 2100.00;
CONSTANTS[68] = 1.00000 - CONSTANTS[19];
CONSTANTS[69] = CONSTANTS[36]/CONSTANTS[37];
CONSTANTS[70] = CONSTANTS[41]/CONSTANTS[39];
}
void
computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[8] = 1.00000/(1.00000+exp((STATES[0]+87.5000)/10.3000));
RATES[10] = (ALGEBRAIC[8] - STATES[10])/CONSTANTS[67];
ALGEBRAIC[1] = 1.00000/(1.00000+exp((STATES[0]+45.0000)/- 6.50000));
ALGEBRAIC[11] = 1.36000/(( 0.320000*(STATES[0]+47.1300))/(1.00000 - exp( - 0.100000*(STATES[0]+47.1300)))+ 0.0800000*exp(- STATES[0]/11.0000));
RATES[2] = (ALGEBRAIC[1] - STATES[2])/ALGEBRAIC[11];
ALGEBRAIC[2] = 1.00000/(1.00000+exp((STATES[0]+76.1000)/6.07000));
ALGEBRAIC[12] = (STATES[0]>=- 40.0000 ? 0.453700*(1.00000+exp(- (STATES[0]+10.6600)/11.1000)) : 3.49000/( 0.135000*exp(- (STATES[0]+80.0000)/6.80000)+ 3.56000*exp( 0.0790000*STATES[0])+ 310000.*exp( 0.350000*STATES[0])));
RATES[3] = (ALGEBRAIC[2] - STATES[3])/ALGEBRAIC[12];
ALGEBRAIC[3] = 1.00000/(1.00000+exp((STATES[0]+76.1000)/6.07000));
ALGEBRAIC[13] = (STATES[0]>=- 40.0000 ? ( 11.6300*(1.00000+exp( - 0.100000*(STATES[0]+32.0000))))/exp( - 2.53500e-07*STATES[0]) : 3.49000/( ((STATES[0]+37.7800)/(1.00000+exp( 0.311000*(STATES[0]+79.2300))))*( - 127140.*exp( 0.244400*STATES[0]) - 3.47400e-05*exp( - 0.0439100*STATES[0]))+( 0.121200*exp( - 0.0105200*STATES[0]))/(1.00000+exp( - 0.137800*(STATES[0]+40.1400)))));
RATES[4] = (ALGEBRAIC[3] - STATES[4])/ALGEBRAIC[13];
ALGEBRAIC[14] = 100.000/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000)));
ALGEBRAIC[4] = 1.00000/(1.00000+exp((STATES[0]+10.6000)/- 11.4200));
RATES[6] = (ALGEBRAIC[4] - STATES[6])/ALGEBRAIC[14];
ALGEBRAIC[15] = 20.0000*exp(- pow((STATES[0]+70.0000)/25.0000, 2.00000))+35.0000;
ALGEBRAIC[5] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410));
RATES[7] = (ALGEBRAIC[5] - STATES[7])/ALGEBRAIC[15];
ALGEBRAIC[16] = 1300.00*exp(- pow((STATES[0]+70.0000)/30.0000, 2.00000))+35.0000;
ALGEBRAIC[6] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410));
RATES[8] = (ALGEBRAIC[6] - STATES[8])/ALGEBRAIC[16];
ALGEBRAIC[17] = 10000.0/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000)));
ALGEBRAIC[7] = 1.00000/(1.00000+exp((STATES[0]+11.5000)/- 11.8200));
RATES[9] = (ALGEBRAIC[7] - STATES[9])/ALGEBRAIC[17];
ALGEBRAIC[18] = 1000.00/( 0.118850*exp((STATES[0]+80.0000)/28.3700)+ 0.562300*exp((STATES[0]+80.0000)/- 14.1900));
ALGEBRAIC[9] = 1.00000/(1.00000+exp((STATES[0]+138.600)/10.4800));
RATES[11] = (ALGEBRAIC[9] - STATES[11])/ALGEBRAIC[18];
ALGEBRAIC[23] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[15]/STATES[5]);
ALGEBRAIC[24] = CONSTANTS[12]*STATES[6]*( CONSTANTS[13]*STATES[7]+ CONSTANTS[14]*STATES[8])*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[25] = CONSTANTS[16]*STATES[9]*STATES[10]*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[26] = ( (0.0480000/(exp((STATES[0]+37.0000)/25.0000)+exp((STATES[0]+37.0000)/- 25.0000))+0.0100000)*0.00100000)/(1.00000+exp((STATES[0] - (ALGEBRAIC[23]+76.7700))/- 17.0000))+( CONSTANTS[17]*(STATES[0] - (ALGEBRAIC[23]+1.73000)))/( (1.00000+exp(( 1.61300*CONSTANTS[2]*(STATES[0] - (ALGEBRAIC[23]+1.73000)))/( CONSTANTS[0]*CONSTANTS[1])))*(1.00000+exp((CONSTANTS[15] - 0.998800)/- 0.124000)));
ALGEBRAIC[31] = CONSTANTS[21]*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[33] = CONSTANTS[23]*pow(1.00000+CONSTANTS[24]/STATES[1], 2.00000)*(1.00000+ (CONSTANTS[25]/STATES[1])*exp((( - CONSTANTS[27]*CONSTANTS[2]*STATES[0])/CONSTANTS[0])/CONSTANTS[1]))+ pow(1.00000+CONSTANTS[28]/CONSTANTS[15], 2.00000)*(1.00000+ (CONSTANTS[11]/CONSTANTS[26])*exp((( - (1.00000 - CONSTANTS[27])*CONSTANTS[2]*STATES[0])/CONSTANTS[0])/CONSTANTS[1]));
ALGEBRAIC[34] = ( CONSTANTS[22]*(CONSTANTS[23]+1.00000))/ALGEBRAIC[33];
ALGEBRAIC[20] = (VOI - floor(VOI/CONSTANTS[4])*CONSTANTS[4]>=0.00000&&VOI - floor(VOI/CONSTANTS[4])*CONSTANTS[4]<=CONSTANTS[5] ? CONSTANTS[6] : 0.00000);
ALGEBRAIC[28] = CONSTANTS[18]*STATES[11]*CONSTANTS[68]*(STATES[0] - ALGEBRAIC[23]);
RATES[5] = ( - (ALGEBRAIC[20]+ALGEBRAIC[25]+ALGEBRAIC[31]+ALGEBRAIC[24]+ALGEBRAIC[26]+ALGEBRAIC[28]+ - 2.00000*ALGEBRAIC[34])*1.00000)/( CONSTANTS[8]*CONSTANTS[2]);
ALGEBRAIC[0] = ( CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1]);
ALGEBRAIC[19] = 2.00000*ALGEBRAIC[0];
ALGEBRAIC[44] = (fabs(ALGEBRAIC[19])>1.00000e-09 ? (STATES[12]+( (CONSTANTS[32]/CONSTANTS[30])*CONSTANTS[29]*ALGEBRAIC[19]*exp(- ALGEBRAIC[19]))/(1.00000 - exp(- ALGEBRAIC[19])))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : (STATES[12]+ (CONSTANTS[32]/CONSTANTS[30])*CONSTANTS[29])/(1.00000+CONSTANTS[32]/CONSTANTS[30]));
ALGEBRAIC[46] = (pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000))/( CONSTANTS[40]*(pow(ALGEBRAIC[44], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[40] = (pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000))/( CONSTANTS[40]*(pow(STATES[12], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[35] = exp((STATES[0] - CONSTANTS[34])/CONSTANTS[35]);
ALGEBRAIC[36] = ALGEBRAIC[35]/( CONSTANTS[37]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[37] = pow(STATES[12], 2.00000)/( CONSTANTS[39]*(pow(STATES[12], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[45] = pow(ALGEBRAIC[44], 2.00000)/( CONSTANTS[39]*(pow(ALGEBRAIC[44], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[52] = (ALGEBRAIC[36]+CONSTANTS[69])*( (CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[45])*(CONSTANTS[70]+ALGEBRAIC[37])+ ALGEBRAIC[36]*(CONSTANTS[70]+ALGEBRAIC[45]));
ALGEBRAIC[53] = ( ALGEBRAIC[36]*CONSTANTS[70]*(ALGEBRAIC[36]+CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[37]))/ALGEBRAIC[52];
ALGEBRAIC[56] = ( CONSTANTS[69]*CONSTANTS[70]*(CONSTANTS[69]+ALGEBRAIC[36]+CONSTANTS[70]+ALGEBRAIC[45]))/ALGEBRAIC[52];
ALGEBRAIC[57] = ALGEBRAIC[53]*ALGEBRAIC[46]+ ALGEBRAIC[56]*ALGEBRAIC[40];
ALGEBRAIC[47] = ( CONSTANTS[42]*CONSTANTS[48]*(pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)))/( CONSTANTS[40]*( CONSTANTS[48]*pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[41] = ( CONSTANTS[42]*CONSTANTS[48]*(pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)))/( CONSTANTS[40]*( CONSTANTS[48]*pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[59] = ( ALGEBRAIC[36]*ALGEBRAIC[47]+ CONSTANTS[69]*ALGEBRAIC[41])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[42] = (STATES[12]+ (CONSTANTS[31]/CONSTANTS[30])*STATES[13])/(1.00000+CONSTANTS[31]/CONSTANTS[30]);
ALGEBRAIC[43] = ( ALGEBRAIC[42]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*CONSTANTS[44]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[38] = ( STATES[12]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*CONSTANTS[44]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[54] = ( CONSTANTS[69]*( ALGEBRAIC[37]*(CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[45])+ ALGEBRAIC[45]*ALGEBRAIC[36]))/ALGEBRAIC[52];
ALGEBRAIC[65] = ALGEBRAIC[54]*ALGEBRAIC[43]+ ALGEBRAIC[56]*ALGEBRAIC[38];
ALGEBRAIC[39] = ( CONSTANTS[46]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*( CONSTANTS[46]*ALGEBRAIC[35]+CONSTANTS[45]));
ALGEBRAIC[67] = ALGEBRAIC[39];
RATES[14] = - (ALGEBRAIC[57]+ALGEBRAIC[65])*STATES[14]+ ALGEBRAIC[59]*STATES[15]+ ALGEBRAIC[67]*STATES[16];
ALGEBRAIC[69] = ( CONSTANTS[69]*ALGEBRAIC[38])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[71] = ALGEBRAIC[39];
ALGEBRAIC[73] = ((1.00000 - STATES[14]) - STATES[15]) - STATES[16];
RATES[15] = ( ALGEBRAIC[57]*STATES[14] - (ALGEBRAIC[59]+ALGEBRAIC[69])*STATES[15])+ ALGEBRAIC[71]*ALGEBRAIC[73];
ALGEBRAIC[61] = ( CONSTANTS[70]*ALGEBRAIC[40])/(CONSTANTS[70]+ALGEBRAIC[37]);
ALGEBRAIC[63] = ALGEBRAIC[41];
RATES[16] = ( ALGEBRAIC[65]*STATES[14] - (ALGEBRAIC[67]+ALGEBRAIC[61])*STATES[16])+ ALGEBRAIC[63]*ALGEBRAIC[73];
ALGEBRAIC[21] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[11]/STATES[1]);
ALGEBRAIC[22] = CONSTANTS[10]*pow(STATES[2], 3.00000)*STATES[3]*STATES[4]*(STATES[0] - ALGEBRAIC[21]);
ALGEBRAIC[30] = CONSTANTS[20]*(STATES[0] - ALGEBRAIC[21]);
ALGEBRAIC[74] = ( CONSTANTS[53]*( exp( CONSTANTS[51]*ALGEBRAIC[0])*pow(STATES[1], 3.00000)*CONSTANTS[29] - exp( (CONSTANTS[51] - 1.00000)*ALGEBRAIC[0])*pow(CONSTANTS[11], 3.00000)*STATES[12]))/( (pow(CONSTANTS[11], 3.00000)+pow(CONSTANTS[49], 3.00000))*(CONSTANTS[29]+CONSTANTS[50])*(1.00000+ CONSTANTS[52]*exp( (CONSTANTS[51] - 1.00000)*ALGEBRAIC[0])));
ALGEBRAIC[75] = ALGEBRAIC[74]*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[27] = CONSTANTS[18]*STATES[11]*CONSTANTS[19]*(STATES[0] - ALGEBRAIC[21]);
RATES[1] = ( - (ALGEBRAIC[22]+ALGEBRAIC[30]+ ALGEBRAIC[75]*3.00000+ ALGEBRAIC[34]*3.00000+ALGEBRAIC[27])*1.00000)/( CONSTANTS[8]*CONSTANTS[2]);
ALGEBRAIC[29] = ALGEBRAIC[27]+ALGEBRAIC[28];
ALGEBRAIC[77] = ( CONSTANTS[56]*STATES[12])/(CONSTANTS[57]+STATES[12]);
ALGEBRAIC[78] = ALGEBRAIC[77]*2.00000*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[51] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( (( CONSTANTS[32]*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*(( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[12])+ (CONSTANTS[31]/CONSTANTS[30])*( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[13])))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(ALGEBRAIC[19]))) : ( (( CONSTANTS[32]*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*(( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[12])+ (CONSTANTS[31]/CONSTANTS[30])*( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[13])))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[50] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( (( CONSTANTS[32]*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[12]))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : ( (( CONSTANTS[32]*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[12]))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[55] = ( ALGEBRAIC[36]*( ALGEBRAIC[45]*(ALGEBRAIC[36]+CONSTANTS[70]+ALGEBRAIC[37])+ ALGEBRAIC[37]*CONSTANTS[69]))/ALGEBRAIC[52];
ALGEBRAIC[66] = ALGEBRAIC[51]*ALGEBRAIC[55]+ ALGEBRAIC[50]*ALGEBRAIC[53];
ALGEBRAIC[68] = ( ALGEBRAIC[50]*ALGEBRAIC[36])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[70] = ( ( STATES[14]*ALGEBRAIC[66]+ STATES[15]*ALGEBRAIC[68])*CONSTANTS[33])/CONSTANTS[7];
ALGEBRAIC[72] = - ALGEBRAIC[70]*2.00000*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[79] = (( CONSTANTS[0]*CONSTANTS[1])/( 2.00000*CONSTANTS[2]))*log(CONSTANTS[29]/STATES[12]);
ALGEBRAIC[80] = CONSTANTS[58]*(ALGEBRAIC[79] - STATES[0]);
ALGEBRAIC[81] = - ALGEBRAIC[80]*2.00000*CONSTANTS[2]*CONSTANTS[8];
RATES[0] = - (ALGEBRAIC[22]+ALGEBRAIC[24]+ALGEBRAIC[25]+ALGEBRAIC[29]+ALGEBRAIC[26]+ALGEBRAIC[30]+ALGEBRAIC[31]+ALGEBRAIC[34]+ALGEBRAIC[81]+ALGEBRAIC[75]+ALGEBRAIC[78]+ALGEBRAIC[72]+ALGEBRAIC[20])/CONSTANTS[3];
ALGEBRAIC[48] = ( CONSTANTS[31]*(STATES[13] - STATES[12]))/(1.00000+CONSTANTS[31]/CONSTANTS[30]);
ALGEBRAIC[49] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( CONSTANTS[31]*((STATES[13] - STATES[12])+ (( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*(STATES[13] - CONSTANTS[29]*exp(- ALGEBRAIC[19]))))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : ( CONSTANTS[31]*((STATES[13] - STATES[12])+ (( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*(STATES[13] - CONSTANTS[29]*exp(- 1.00000e-05))))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[58] = ALGEBRAIC[55]*ALGEBRAIC[49]+ ALGEBRAIC[48]*ALGEBRAIC[54];
ALGEBRAIC[60] = ( ALGEBRAIC[48]*ALGEBRAIC[37])/(CONSTANTS[70]+ALGEBRAIC[37]);
ALGEBRAIC[62] = ( ( STATES[14]*ALGEBRAIC[58]+ STATES[16]*ALGEBRAIC[60])*CONSTANTS[33])/CONSTANTS[7];
ALGEBRAIC[64] = ALGEBRAIC[62];
ALGEBRAIC[76] = ( CONSTANTS[54]*pow(STATES[12], 2.00000))/(pow(CONSTANTS[55], 2.00000)+pow(STATES[12], 2.00000));
ALGEBRAIC[82] = CONSTANTS[59]*(STATES[13] - STATES[12]);
RATES[13] = (CONSTANTS[8]/CONSTANTS[9])*((- ALGEBRAIC[64]+ALGEBRAIC[76]) - ALGEBRAIC[82]);
ALGEBRAIC[83] = CONSTANTS[60]*(CONSTANTS[62] - STATES[17]) - CONSTANTS[61]*STATES[17]*STATES[12];
RATES[17] = ALGEBRAIC[83];
ALGEBRAIC[84] = pow(1.00000+( CONSTANTS[63]*CONSTANTS[64])/pow(CONSTANTS[63]+STATES[12], 2.00000)+( CONSTANTS[65]*CONSTANTS[66])/pow(CONSTANTS[66]+STATES[12], 2.00000), - 1.00000);
RATES[12] = ALGEBRAIC[84]*(((ALGEBRAIC[64] - ALGEBRAIC[76])+ALGEBRAIC[82]+ALGEBRAIC[83]) - ( - 2.00000*ALGEBRAIC[75]+ALGEBRAIC[72]+ALGEBRAIC[78]+ALGEBRAIC[81])/( 2.00000*CONSTANTS[8]*CONSTANTS[2]));
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[8] = 1.00000/(1.00000+exp((STATES[0]+87.5000)/10.3000));
ALGEBRAIC[1] = 1.00000/(1.00000+exp((STATES[0]+45.0000)/- 6.50000));
ALGEBRAIC[11] = 1.36000/(( 0.320000*(STATES[0]+47.1300))/(1.00000 - exp( - 0.100000*(STATES[0]+47.1300)))+ 0.0800000*exp(- STATES[0]/11.0000));
ALGEBRAIC[2] = 1.00000/(1.00000+exp((STATES[0]+76.1000)/6.07000));
ALGEBRAIC[12] = (STATES[0]>=- 40.0000 ? 0.453700*(1.00000+exp(- (STATES[0]+10.6600)/11.1000)) : 3.49000/( 0.135000*exp(- (STATES[0]+80.0000)/6.80000)+ 3.56000*exp( 0.0790000*STATES[0])+ 310000.*exp( 0.350000*STATES[0])));
ALGEBRAIC[3] = 1.00000/(1.00000+exp((STATES[0]+76.1000)/6.07000));
ALGEBRAIC[13] = (STATES[0]>=- 40.0000 ? ( 11.6300*(1.00000+exp( - 0.100000*(STATES[0]+32.0000))))/exp( - 2.53500e-07*STATES[0]) : 3.49000/( ((STATES[0]+37.7800)/(1.00000+exp( 0.311000*(STATES[0]+79.2300))))*( - 127140.*exp( 0.244400*STATES[0]) - 3.47400e-05*exp( - 0.0439100*STATES[0]))+( 0.121200*exp( - 0.0105200*STATES[0]))/(1.00000+exp( - 0.137800*(STATES[0]+40.1400)))));
ALGEBRAIC[14] = 100.000/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000)));
ALGEBRAIC[4] = 1.00000/(1.00000+exp((STATES[0]+10.6000)/- 11.4200));
ALGEBRAIC[15] = 20.0000*exp(- pow((STATES[0]+70.0000)/25.0000, 2.00000))+35.0000;
ALGEBRAIC[5] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410));
ALGEBRAIC[16] = 1300.00*exp(- pow((STATES[0]+70.0000)/30.0000, 2.00000))+35.0000;
ALGEBRAIC[6] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410));
ALGEBRAIC[17] = 10000.0/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000)));
ALGEBRAIC[7] = 1.00000/(1.00000+exp((STATES[0]+11.5000)/- 11.8200));
ALGEBRAIC[18] = 1000.00/( 0.118850*exp((STATES[0]+80.0000)/28.3700)+ 0.562300*exp((STATES[0]+80.0000)/- 14.1900));
ALGEBRAIC[9] = 1.00000/(1.00000+exp((STATES[0]+138.600)/10.4800));
ALGEBRAIC[23] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[15]/STATES[5]);
ALGEBRAIC[24] = CONSTANTS[12]*STATES[6]*( CONSTANTS[13]*STATES[7]+ CONSTANTS[14]*STATES[8])*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[25] = CONSTANTS[16]*STATES[9]*STATES[10]*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[26] = ( (0.0480000/(exp((STATES[0]+37.0000)/25.0000)+exp((STATES[0]+37.0000)/- 25.0000))+0.0100000)*0.00100000)/(1.00000+exp((STATES[0] - (ALGEBRAIC[23]+76.7700))/- 17.0000))+( CONSTANTS[17]*(STATES[0] - (ALGEBRAIC[23]+1.73000)))/( (1.00000+exp(( 1.61300*CONSTANTS[2]*(STATES[0] - (ALGEBRAIC[23]+1.73000)))/( CONSTANTS[0]*CONSTANTS[1])))*(1.00000+exp((CONSTANTS[15] - 0.998800)/- 0.124000)));
ALGEBRAIC[31] = CONSTANTS[21]*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[33] = CONSTANTS[23]*pow(1.00000+CONSTANTS[24]/STATES[1], 2.00000)*(1.00000+ (CONSTANTS[25]/STATES[1])*exp((( - CONSTANTS[27]*CONSTANTS[2]*STATES[0])/CONSTANTS[0])/CONSTANTS[1]))+ pow(1.00000+CONSTANTS[28]/CONSTANTS[15], 2.00000)*(1.00000+ (CONSTANTS[11]/CONSTANTS[26])*exp((( - (1.00000 - CONSTANTS[27])*CONSTANTS[2]*STATES[0])/CONSTANTS[0])/CONSTANTS[1]));
ALGEBRAIC[34] = ( CONSTANTS[22]*(CONSTANTS[23]+1.00000))/ALGEBRAIC[33];
ALGEBRAIC[20] = (VOI - floor(VOI/CONSTANTS[4])*CONSTANTS[4]>=0.00000&&VOI - floor(VOI/CONSTANTS[4])*CONSTANTS[4]<=CONSTANTS[5] ? CONSTANTS[6] : 0.00000);
ALGEBRAIC[28] = CONSTANTS[18]*STATES[11]*CONSTANTS[68]*(STATES[0] - ALGEBRAIC[23]);
ALGEBRAIC[0] = ( CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1]);
ALGEBRAIC[19] = 2.00000*ALGEBRAIC[0];
ALGEBRAIC[44] = (fabs(ALGEBRAIC[19])>1.00000e-09 ? (STATES[12]+( (CONSTANTS[32]/CONSTANTS[30])*CONSTANTS[29]*ALGEBRAIC[19]*exp(- ALGEBRAIC[19]))/(1.00000 - exp(- ALGEBRAIC[19])))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : (STATES[12]+ (CONSTANTS[32]/CONSTANTS[30])*CONSTANTS[29])/(1.00000+CONSTANTS[32]/CONSTANTS[30]));
ALGEBRAIC[46] = (pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000))/( CONSTANTS[40]*(pow(ALGEBRAIC[44], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[40] = (pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000))/( CONSTANTS[40]*(pow(STATES[12], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[35] = exp((STATES[0] - CONSTANTS[34])/CONSTANTS[35]);
ALGEBRAIC[36] = ALGEBRAIC[35]/( CONSTANTS[37]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[37] = pow(STATES[12], 2.00000)/( CONSTANTS[39]*(pow(STATES[12], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[45] = pow(ALGEBRAIC[44], 2.00000)/( CONSTANTS[39]*(pow(ALGEBRAIC[44], 2.00000)+pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[52] = (ALGEBRAIC[36]+CONSTANTS[69])*( (CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[45])*(CONSTANTS[70]+ALGEBRAIC[37])+ ALGEBRAIC[36]*(CONSTANTS[70]+ALGEBRAIC[45]));
ALGEBRAIC[53] = ( ALGEBRAIC[36]*CONSTANTS[70]*(ALGEBRAIC[36]+CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[37]))/ALGEBRAIC[52];
ALGEBRAIC[56] = ( CONSTANTS[69]*CONSTANTS[70]*(CONSTANTS[69]+ALGEBRAIC[36]+CONSTANTS[70]+ALGEBRAIC[45]))/ALGEBRAIC[52];
ALGEBRAIC[57] = ALGEBRAIC[53]*ALGEBRAIC[46]+ ALGEBRAIC[56]*ALGEBRAIC[40];
ALGEBRAIC[47] = ( CONSTANTS[42]*CONSTANTS[48]*(pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)))/( CONSTANTS[40]*( CONSTANTS[48]*pow(ALGEBRAIC[44], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[41] = ( CONSTANTS[42]*CONSTANTS[48]*(pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)))/( CONSTANTS[40]*( CONSTANTS[48]*pow(STATES[12], 2.00000)+ CONSTANTS[47]*pow(CONSTANTS[43], 2.00000)));
ALGEBRAIC[59] = ( ALGEBRAIC[36]*ALGEBRAIC[47]+ CONSTANTS[69]*ALGEBRAIC[41])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[42] = (STATES[12]+ (CONSTANTS[31]/CONSTANTS[30])*STATES[13])/(1.00000+CONSTANTS[31]/CONSTANTS[30]);
ALGEBRAIC[43] = ( ALGEBRAIC[42]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*CONSTANTS[44]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[38] = ( STATES[12]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*CONSTANTS[44]*(ALGEBRAIC[35]+1.00000));
ALGEBRAIC[54] = ( CONSTANTS[69]*( ALGEBRAIC[37]*(CONSTANTS[69]+CONSTANTS[70]+ALGEBRAIC[45])+ ALGEBRAIC[45]*ALGEBRAIC[36]))/ALGEBRAIC[52];
ALGEBRAIC[65] = ALGEBRAIC[54]*ALGEBRAIC[43]+ ALGEBRAIC[56]*ALGEBRAIC[38];
ALGEBRAIC[39] = ( CONSTANTS[46]*(ALGEBRAIC[35]+CONSTANTS[45]))/( CONSTANTS[38]*( CONSTANTS[46]*ALGEBRAIC[35]+CONSTANTS[45]));
ALGEBRAIC[67] = ALGEBRAIC[39];
ALGEBRAIC[69] = ( CONSTANTS[69]*ALGEBRAIC[38])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[71] = ALGEBRAIC[39];
ALGEBRAIC[73] = ((1.00000 - STATES[14]) - STATES[15]) - STATES[16];
ALGEBRAIC[61] = ( CONSTANTS[70]*ALGEBRAIC[40])/(CONSTANTS[70]+ALGEBRAIC[37]);
ALGEBRAIC[63] = ALGEBRAIC[41];
ALGEBRAIC[21] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[11]/STATES[1]);
ALGEBRAIC[22] = CONSTANTS[10]*pow(STATES[2], 3.00000)*STATES[3]*STATES[4]*(STATES[0] - ALGEBRAIC[21]);
ALGEBRAIC[30] = CONSTANTS[20]*(STATES[0] - ALGEBRAIC[21]);
ALGEBRAIC[74] = ( CONSTANTS[53]*( exp( CONSTANTS[51]*ALGEBRAIC[0])*pow(STATES[1], 3.00000)*CONSTANTS[29] - exp( (CONSTANTS[51] - 1.00000)*ALGEBRAIC[0])*pow(CONSTANTS[11], 3.00000)*STATES[12]))/( (pow(CONSTANTS[11], 3.00000)+pow(CONSTANTS[49], 3.00000))*(CONSTANTS[29]+CONSTANTS[50])*(1.00000+ CONSTANTS[52]*exp( (CONSTANTS[51] - 1.00000)*ALGEBRAIC[0])));
ALGEBRAIC[75] = ALGEBRAIC[74]*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[27] = CONSTANTS[18]*STATES[11]*CONSTANTS[19]*(STATES[0] - ALGEBRAIC[21]);
ALGEBRAIC[29] = ALGEBRAIC[27]+ALGEBRAIC[28];
ALGEBRAIC[77] = ( CONSTANTS[56]*STATES[12])/(CONSTANTS[57]+STATES[12]);
ALGEBRAIC[78] = ALGEBRAIC[77]*2.00000*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[51] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( (( CONSTANTS[32]*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*(( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[12])+ (CONSTANTS[31]/CONSTANTS[30])*( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[13])))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(ALGEBRAIC[19]))) : ( (( CONSTANTS[32]*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*(( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[12])+ (CONSTANTS[31]/CONSTANTS[30])*( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[13])))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[50] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( (( CONSTANTS[32]*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*( CONSTANTS[29]*exp(- ALGEBRAIC[19]) - STATES[12]))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : ( (( CONSTANTS[32]*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*( CONSTANTS[29]*exp(- 1.00000e-05) - STATES[12]))/(1.00000+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[55] = ( ALGEBRAIC[36]*( ALGEBRAIC[45]*(ALGEBRAIC[36]+CONSTANTS[70]+ALGEBRAIC[37])+ ALGEBRAIC[37]*CONSTANTS[69]))/ALGEBRAIC[52];
ALGEBRAIC[66] = ALGEBRAIC[51]*ALGEBRAIC[55]+ ALGEBRAIC[50]*ALGEBRAIC[53];
ALGEBRAIC[68] = ( ALGEBRAIC[50]*ALGEBRAIC[36])/(ALGEBRAIC[36]+CONSTANTS[69]);
ALGEBRAIC[70] = ( ( STATES[14]*ALGEBRAIC[66]+ STATES[15]*ALGEBRAIC[68])*CONSTANTS[33])/CONSTANTS[7];
ALGEBRAIC[72] = - ALGEBRAIC[70]*2.00000*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[79] = (( CONSTANTS[0]*CONSTANTS[1])/( 2.00000*CONSTANTS[2]))*log(CONSTANTS[29]/STATES[12]);
ALGEBRAIC[80] = CONSTANTS[58]*(ALGEBRAIC[79] - STATES[0]);
ALGEBRAIC[81] = - ALGEBRAIC[80]*2.00000*CONSTANTS[2]*CONSTANTS[8];
ALGEBRAIC[48] = ( CONSTANTS[31]*(STATES[13] - STATES[12]))/(1.00000+CONSTANTS[31]/CONSTANTS[30]);
ALGEBRAIC[49] = (fabs(ALGEBRAIC[19])>1.00000e-05 ? ( CONSTANTS[31]*((STATES[13] - STATES[12])+ (( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19])))*(STATES[13] - CONSTANTS[29]*exp(- ALGEBRAIC[19]))))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*ALGEBRAIC[19])/(1.00000 - exp(- ALGEBRAIC[19]))) : ( CONSTANTS[31]*((STATES[13] - STATES[12])+ (( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05)))*(STATES[13] - CONSTANTS[29]*exp(- 1.00000e-05))))/(1.00000+CONSTANTS[31]/CONSTANTS[30]+( (CONSTANTS[32]/CONSTANTS[30])*1.00000e-05)/(1.00000 - exp(- 1.00000e-05))));
ALGEBRAIC[58] = ALGEBRAIC[55]*ALGEBRAIC[49]+ ALGEBRAIC[48]*ALGEBRAIC[54];
ALGEBRAIC[60] = ( ALGEBRAIC[48]*ALGEBRAIC[37])/(CONSTANTS[70]+ALGEBRAIC[37]);
ALGEBRAIC[62] = ( ( STATES[14]*ALGEBRAIC[58]+ STATES[16]*ALGEBRAIC[60])*CONSTANTS[33])/CONSTANTS[7];
ALGEBRAIC[64] = ALGEBRAIC[62];
ALGEBRAIC[76] = ( CONSTANTS[54]*pow(STATES[12], 2.00000))/(pow(CONSTANTS[55], 2.00000)+pow(STATES[12], 2.00000));
ALGEBRAIC[82] = CONSTANTS[59]*(STATES[13] - STATES[12]);
ALGEBRAIC[83] = CONSTANTS[60]*(CONSTANTS[62] - STATES[17]) - CONSTANTS[61]*STATES[17]*STATES[12];
ALGEBRAIC[84] = pow(1.00000+( CONSTANTS[63]*CONSTANTS[64])/pow(CONSTANTS[63]+STATES[12], 2.00000)+( CONSTANTS[65]*CONSTANTS[66])/pow(CONSTANTS[66]+STATES[12], 2.00000), - 1.00000);
ALGEBRAIC[10] = STATES[12];
ALGEBRAIC[32] = ALGEBRAIC[30]+ALGEBRAIC[31];
}